Under Construction

MN Current Process:

• 100 people looking at evidence on 25 targets - EBM Team
• Librarians running searches on different databased in different intervals. Ad hoc identify important papers that generate press. [Sandy - use DocSearch to identify this new information - searches clinicaltrials.gov, health rss feeds, WHO databases, pubmed, etc.]
• EBM team reviews literature, updates recommendations. Content expert team/system ops team decides what gets implemented. Teams are separate but trying to optimize going forward.
• Going forward, plan to coordinate more closely with EPC. They set up alerts about new info. Manually update SRDR with this new information. SS has team that makes ultimate decision.
  • MN EPC looking at how to abstract information from studies better to update guideline. How to automate processes better (PICO processing). 
  • What kind of tools are available to support more standard/excel data capture to speed up structuring of data pulled from reviews. Or does UMN need to create the structured file for input into SRDR. Looking at published trials and also studies underway. (3 ways to get data into SRDR: 1) abstract from studies as they are reviewed, 2) input from other systems (Distillr SR/excel) - most common).
  • interested in ML/NLP support for screening process - look at a wider set of study designs. Prioritize what will be helpful for the topic. (Abstractor builds a model to see if something is relevant to a target (deep learning/neural networks) - presents to user for screening. Being rolled into SRDR.) They are watching COVID-NMA, but not using it in their work at this point. Considering supporting anticoagulation for COVID-NMA work.

MN Enhanced Process:

For Anticoagulation - optimize work/output of people/process/technology:

DocSearch -> L*VE/Epistemonikos → Abstractor -> SRDR -> COVID-NMA > AU Living Guidelines → C19 Digital Guideline WG - UMN CDS Implementation Team → Evaluation → [back to beginning]

[How secure are funding sources for these efforts? How resilient are these. Idea is to map out a cross-cutting enhancement approach and how it's being implemented in individual sites. Provide additional information (links, descriptions, regular meetings, perhaps webinars) so everyone can learn more about the individual components and how they are being combined.]