Korábbi változatok

• includes evaluation of quality of evidence 
• also needs to address processing of real world evidence
• [weave in ICER - search ISER opioids]

• For people creating evidence syntheses
  • See if work on planned topic has been done already - search L*VE/Epistemonikos (2K reviews - cover many questions - only a fraction registered in PROSPERO; most reviews are out of date - only 3% have all the trials they should), PROSPERO for what's in the pipeline. Make sure that any existing reviews look at outcomes that are pertinent to your needs [leverage COMET - outcome measures], etc. that of interest for the need at hand. Very hard for user to identify a review that's up to date. COVID-END repository of Best Evidence Syntheses can be helpful here.
  • Need to have access to raw data that fed into the review so it's more re-usable.
  • important to understand end-user needs so that the review can be aimed at addressing them
  • AHRQ has methods guides, Cochrane has them. Are there tools for this on COVID - e.g., Resources and tools for researchers considering and conducting
    COVID-19 evidence syntheses (From COVID-END Synthesizing WG)
• For organizations consuming evidence syntheses
  • For selecting/using synthesized evidence: Is there a GRADE evidence profile? Do they make quality assessments? How comprehensive are they? Search date

• See Sources/Repositories from Identify Studies table
• ClinicalTrials.gov/COVID-19; New pubmed interface; DoctorEvidence CORD-19 Dataset Search
• PROSPERO

• Underlying justification and evidence tables (critically ill and acutely ill) from ASH Anticoagulation Living Guidelines
• L*VE/Epistemonikos search on antithrombotics; can send email when new study/review/guideline is published.
• Rapid Cochrane review on anticoagulation in COVID-19 patients

• BMJ EBM rapid review on COVID tests

• SRDR+
• COVID NMA Project
• COVID-END Best Evidence Syntheses Inventory ('best evidence syntheses' on clinical management)
  • reviews that are living, up to date, high quality and where there is a GRADE evidence profile. 
• LIVING Project - living systematic review of COVID-19 interventions;
• L*VE/Epistemonikos, 
• VA COVID-19 Evidence Reviews;
• GIN COVID-19 Evidence Resources
• EvidenceAid
• Usher Network for COVID-19 Evidence Reviews

• IOM Report: Finding What Works in Health Care:  Standards for Systematic Reviews
• EBM on FHIR/COKA COKA (standards include: Evidence, EvidenceReport, EvidenceVariable, Group, Citation
• Vocabulary Map for Evidence-related resources[ Project Google Drive])
• AGREE II for rating the quality of guidelines
• [Add AMSTAR and all study quality rating tools here]

• COKA Steroids for COVID-19 Systematic Meta-Review Protocol; slides about this effort

• Resources and tools for researchers considering and conducting
  COVID-19 evidence syntheses (From COVID-END Synthesizing WG)
• GIN COVID-19 Evidence Resources
• SRDR+, Covidence, Distiller SR, RevMan, JBI Sumari
• Doctor Evidence Analytics Tool

• COVID-NMA has initiated communication AHRQ EPC Methods Guides
• COMET (Core Outcome Measures in Effectiveness Trials
• Equator Network: Enhancing the QUAlity and Transparency Of health Research

• COVID-NMA has initiated communication with all trialists to try to ensure consistent approaches e.g. selection of outcomes, reduction of risk of bias, and to invite them to contribute missing data. 
• Framework slides: Applying Standards to the Evidence Domain (from the COKA Evidence Ecosystem Liaison WG)

For people using or consuming guidance:

• COVID-END Inventory of Resources to Support Decisionmakers for evidence on public health measures, clinical management, health systems, and social and economic issues
• GIN Library of Guidelines – to search for completed, planned, or in-development guidelines
• ECRI COVID-19 Guideline Resources and ECRI Library for the full repository of guidelines
• AGREE II for rating the quality of guidelines

For people producing guidance:

• GIN Library to register guidelines in process
• PICO(TTS) paradigm
• GRADEpro GDT
• WHO-INTEGRATE evidence to decision framework
• EtD Framework
• mDelphi surveys to achieve consensus
• GRADE for grading recs
• GIN-McMaster Guideline Development Checklist
• WHO Handbook for Guideline Development
• Many medical professional societies develop guidelines and each has their own manual, available on the society’s website and/or published in their journal

• See Output Repositories from Synthesize Evidence table

• ASH Living Guideline on COVID anticoagulation and underlying justification and evidence tables (critically ill and acutely ill)
• NIH Guideline
• AU living Guideline
• NEJM vignette with expert opinion

• BMJ/Remote Triage in Ambulatory Care

• Living Map of COVID-19 recommendations (Canadian Institutes of Health Research)
• ECRI COVID-19 Guideline Resources
• GIN will publish (has published?) a registry of guidelines in development (COVID and beyond)

IOM Standards: Clinical Practice Guidelines We Can Trust

• GIN COVID-19 Guidance Resources
• MAGICapp; 
• COVID-END Rapid Response Model and Tips/Tools
• GRADE
• International Patient Decision Aid Standards
• 9/15/20 Annals IM article on COVID guidelines. 
• AGREE II for assessing guideline quality and reporting;
• Africa Centre for Evidence Living Hub of COVID-19 Knowledge Hubs

• COVID-END Recommending WG guidance on producing COVID-19 Guidelines [to be released soon]
• 2011 NAM (IOM) Standards for Guidelines
• Guideline development resources: GIN/McMaster Checklist, Australia Guidelines for Guidelines Handbook
• Methodologies for the Development of CHEST Guidelines and Expert Panel Reports